On Cirkan-treated patients, after 4 weeks, CD decreased on both limbs and CM improved on the left one, suggesting an amelioration of the chronic venous hypertension. No significant changes could be detected on other patient groups. Using orthogonal polarization spectral technique (noninvasive method), measurements of functional capillary density (FCD, number of capillaries with flowing red blood cells/mm(2)), capillary morphology (CM, % of abnormal capillaries/mm(2)) and diameters (mum) of dermal papilla (DDP), capillary bulk (DCB) and capillary limb (CD) were obtained on the medial perimalleolar region and later analyzed using CapImage software. RESULTS AND CONCLUSIONS: CVD patients showed significant changes on CD and CM compared to healthy subjects in agreement with our previous findings (J Vasc Surg 43:1037-1044, 2006). Ten healthy women age-matched were also investigated. Source 1: Use of microcirculatory parameters to evaluate clinical treatments of chronic venous disorder (CVD).Ībstract 1: OBJECTIVES: To evaluate changes on cutaneous microangiopathy in chronic venous disorder (CVD) after use of Cirkan, elastic compression stockings (ECS) or no treatment for four weeks. PATIENTS AND METHODS: Fifty-five female patients (85 legs), 25 to 57 years, with at least one limb classified as C2,s or C2,3,s (CEAP classification), were allocated consecutively, according to entrance order, in these three groups. The combination of ruscus aculeatus, vitamin C (ascorbic acid) and hesperidin has been found to improve capillary structure and chronic venous hypertension, and for these reasons it is ideal for inclusion in anti-cellulite / leg wellness creams. Hesperidin, ascorbic acid and butcher's broom improve vein function and circulation Of course, hyaluronidase and elastase inhibition are only two of the many different ways in which those three well researched and widely used plants help protect blood vessels and boost circulation / lymphatic drainage.

The study has shown that ruscogenin from butcher's broom was very effective in preventing the breakdown of elastin but ineffective in protecting hyaluronic acid escin from horse chestnut was effective only in protecting hyaluronic acid oleanolic acid and hederagenin from ivy are effective in preventing the breakdown of elastin as well as hyaluronic acid. In this study scientists examined how effective these three herbs and their active chemicals were in fighting the breakdown of elastin and hyaluronic acid, both very important components of the basic substance that surrounds and protects blood vessels. Oral supplementation with may prevent time-consuming, painful, and expensive complications of varicose veins and hemorrhoidsġ/ ruscus aculeatus / ruscogenin protects blood vessels by preventing the breakdown of elastin Several botanical extracts (horse chestnut/aesculus, butcher's broom/ruscus, gotu kola, flavonoids and pine bark) have been shown to improve microcirculation, capillary flow and vascular tone, and to strengthen the connective tissue of the perivascular amorphous substrate. The loss of vascular integrity is associated with the pathogenesis of varicose veins.

In patients who applied both the cream and the compression garment pain stopped in 72 hours, inflammation disappeared in one week, tissue swelling stopped in one week and healing was complete in 4 weeks.Ģ/ Review paper suggests butcher's broom for the treatment of varicose veins Ivy extract in the cream contributed to pain reduction horse chestnut, butcher's broom and grape seed extract reduced inflammation and allantoin, gotu kola and hyaluronic acid aided sore healing. This herbal compound, in combination with compression garments, significantly improved inflammation, healing time and pain in phlebitis, in relation to compression garments alone. In comparison to diosmin, ruscus is more effective and its results last longer.ģ/ Phlebitis ulcers heal with the aid of herbal cream consisting of horse chestnut, butcher's broom, allantoin and hyaluronic acid helps fight water retention, under-eye bags and celluliteĤ/ Ruscus aculeatus improves venulre contraction and protects veins from histamine-induced hyper-permeability.

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